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This paper presents a comparative study of blood donation policies in force in the United States, Canada, Denmark, Australia, Uganda, and Singapore which demonstrate the balance between effective health policy and individual rights norms. This study examines national public health policy formulation and implementation, specifically focusing on how the paradigms of law and epidemiology are reconciled to create effective public health policies. Especially since the diagnosis and identification of human immunodeficiency virus HIV and its end-stage disease acquired immune deficiency syndrome AIDS , national governments, often in concert with non-governmental organizations, have sought to guarantee safe blood supplies.